Boskone is simply one of the best lit-SF cons around, and I go every year I can. I've met two of my closest friends there, and attended some of the best programming on books, science, or fandom. Not to mention that their dealer's room is primo. I don't know yet if I can make it up to Boston this year, but I'm hopeful. By the way, their guests this year are pretty awesome.

(Source: NESFA)